The Manager Set Schedule feature is available for NFL and NCAA Pickem leagues. It is especially useful for NCAA leagues that can have 50+ games on the schedule for any given week during the regular season.
Note that you must first enable the feature in the Manager -> League Settings page. It is enabled by default when creating an NCAA league.
The Manager Set Schedule is available in the Manager pull-down, or on the the full control panel as shown below.
On the Set Schedule page you can select specific games for your league that will appear on the My Picks page. You can also optionally assign point values for each game.